Sandra Kane-Gill 2021

Pitt Pharmacy professor Sandra Kane-Gill, PharmD, MS, FCCM, FCCP, was recently awarded two grants from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The first – a R01 grant for the project entitled, “Multi-hospital Implementation of an Electronic Decision Support System for Drug-associated AKI”, in which she is a co-principal investigator. Co-investigators include Pitt Pharmacy faculty members Dr. Colleen Culley, PharmD, BCPS; Dr. Pamela Smithburger PharmD, MS, BCPS, BCCCP, FCCP, FCCM; and Dr. Alexis Gaggini, PharmD. The project will assess the effectiveness of a clinical surveillance alert system augmented with real-time EMR predictive analytics to support a pharmacist-led intervention to reduce the progression and complications of Drug-associated Acute Kidney Injury. This work advances Kane-Gill’s research program theme of medication safety and nephrotoxin stewardship.

The second grant focuses on processes of care after AKI hospitalization, which have been found to be suboptimal – with lack of continuity of care, delayed follow-up, and suboptimal medication management exacerbating the risks of adverse outcomes. The Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Consortium – which includes NIDDK, Cleveland Clinic, John Hopkins University and the Vanderbilt University Medical Center – will develop and test interventions to optimize processes of care and identify key pharmacologic and non-pharmacologic interventions to reduce morbidity among these high-risk patients.

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