Summary: A panel of U.S. experts has developed treatment guidelines for COVID-19. The document provides background information about each pharmacologic therapy (antivirals, host modifiers, and immune-based therapies) —such as clinical data about its use, ongoing clinical trials, and known interactions with other drugs. Importantly, the guidelines state that no COVID-19 medication has been conclusively shown to be safe and effective, but they do recommend against the use of hydroxychloroquine plus azithromycin (toxicity potential), lopinavir/ritonavir or other HIV protease inhibitors (pharmacodynamics and negative clinical trial data), interferons (suspected lack of efficacy and toxicity), and Janus kinase inhibitors (immunosuppression).
Information current as of 04/21/2020
Organization: National Institutes of Health (NIH)
Title: Expert U.S. panel develops NIH treatment guidelines for COVID-19
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